What exactly is androskat?
andros cat is a so-called tri-mix injectionA sterile solution containing papaverine (a smooth muscle relaxant), phentolamine (α-blocker), and alprostadil (prostaglandin E1). The three substances work synergistically; relatively low doses are required, reducing the risk of side effects compared to monotherapy (papayerine alone). Clinical series from the 1990s already showed that 35 out of 35 men achieved a usable erection with similar tri-mix formulas (PubMed). Recent Dutch protocols use virtually the same ratios under the brand name andros cat.
This is how androskat works in the body
Papaverine and alprostadil increase cAMP and cGMP in the smooth muscle of the corpora cavernosa, while phentolamine decreases α-adrenergic tone. The result: maximal vasodilatory conditions, which allow blood to flow in and out. Papaverine as a single agent can be effective. Mayo Clinic, but combination injections such as androskat produce a firmer erection with smaller volumes and less chance of priapism.
Who is Androskat for?
- PDE-5 inhibitor-resistant ED – men who do not respond adequately to sildenafil or tadalafil.
- Post-prostatectomy patients – in case of nerve damage, androskat can bridge the gap to spontaneous erections.
- Diabetes-related vascular ED – when microangiopathy limits PDE-5 function.
- Hormonal or psychogenic ED where fast, reliable stiffness is required to build successful experiences.
Always ask a urologist for a test injection in the clinic before using Androskat at home; correct dose titration is crucial to avoid complications.
8 Tips for Safe Use in 2025
# | Tip | Why important? |
---|---|---|
1 | Start with 0.25 ml | This reduces the risk of priapism (erection > 4 hours). |
2 | Change injection side | Prevents fibrosis and nodules in the erectile tissues. |
3 | Use ultra-thin 30G needles | Minimizes pain and bleeding. |
4 | Inject at the 10 o'clock or 2 o'clock position | Avoid the large dorsal nerve and vascular cord. |
5 | Massage after injection | Distribute the fluid for even action. |
6 | Max. 3 times per week | Tissue needs time to heal; overdosing will cause scarring. |
7 | Learn priapism protocol | Sudden cold pack + 60 mg pseudoephedrine; if necessary, emergency department for aspiration. |
8 | Integrate pelvic floor training | Improves venous occlusion, allowing androskat to be used at a lower dose in the long term. |
Possible side effects of Androskat and how to prevent them
- Priapism (erection > 4 hours) – occurs at ± 3 %; prevent it with careful dosing and tip 7 above.
- Penile pain – usually mild and temporary; use EMLA cream or choose a smaller needle.
- Hematomas or plaque formation – rotate injection sites and keep needle perpendicular.
- Systemic hypotension – rare; remain lying down during the first test injection.
Androskat versus Trimix from the US
Trimix formulations vary (5–30 µg alprostadil). Androskat uses a fixed distribution embedded in the European Pharmacopoeia. Both drugs share the "three-pillar" philosophy, but Androskat is available by prescription through Dutch pharmacies and is subject to a local quality protocol – an advantage in terms of traceability and consistency. Gameday Men's Health - US.
Combine or switch?
- With PDE-5 inhibitors – not on the same day; the combination may lower blood pressure too much.
- With vacuum pump – 10 min vacuum pump before injection dilutes the insertion depth and may allow for a lower dosage of androskat.
- Switch to bimix (papaverine + phentolamine) if you experience PGE1-related pain; the success rate is slightly lower, but comfort may increase Memorial Sloan Kettering Cancer Center.
Psychological and relational dimension
Injection therapy can sometimes evoke resistance or embarrassment. Discuss your feelings with your partner and/or sex therapist; couples who go through the treatment steps together report higher adherence and greater sexual satisfaction. Realize that androskat is only a tool; emotional connection and arousal remain essential.
Is Androskat for me?
By 2025, androskat will be a powerful, targeted solution for men who fail oral medication. Strict dosing protocols, proper injection technique, and additional lifestyle and psychological interventions keep the risk of complications low. The 8 tips above will not only increase its effectiveness but also your ease of use and self-confidence.
Product tip: Cenforce 200mg
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Disclaimer: This article is for informational purposes only and does not replace medical advice. Always consult your doctor before starting Androskat or any other medication.